MMP 8 His Recombinant Protein
Product Sizes
20 µg
£528.00
32-2553-20UG
About this Product
- SKU:
- 32-2553
- Additional Names:
- CLG1||HNC||MMP-8||PMNL-CL||Neutrophil collagenase||Matrix metalloproteinase-8||MMP-8||PMNL collagenase.
- Extra Details:
- Source : Escherichia Coli. MMP 8 Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 390 amino acids (101-467a.a) and having a molecular mass of 44.3kDa. MMP 8 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Full-length recombinant human neutrophil pro-collagenase (MMP-8); latent form.Matrix metalloproteinase 8 (MMP-8); or neutrophil collagenase; degrades interstitial collagens; acting preferentially on collagen type I. Increased full-length MMP-8 protein was associated with infiltration into the skin of neutrophils; which are the major cell type that expresses MMP-8.MMP-8 is synthesized and stored in specific granules in neutrophil leukocytes. MMP-8 activity is therefore regulated by factors such as surface-bound ligands (IgG or complement components) that release it through degranulation.Once released and activated through proteolytic or oxidative mechanisms; MMP-8 plays a major role in the connective tissue turnover that accompanies inflammatory processes.
- Purification:
- Greater than 85% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Assay Kits:MMP
- Manufacturer's Data Sheet:1.jpg
