MMP 8 Recombinant Protein
Product Sizes
2.5U
£631.00
32-2552-2.5U
About this Product
- SKU:
- 32-2552
- Additional Names:
- Neutrophil collagenase||EC 3.4.24.34||Matrix metalloproteinase-8||MMP-8||PMNL collagenase||PMNL-CL||HNC||CLG1.
- Extra Details:
- Source : Escherichia Coli. Matrix Metalloproteinase-8 Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain having a molecular mass of 75 kDa.The MMP-8 is purified by proprietary chromatographic techniques. Full-length recombinant human neutrophil pro-collagenase (MMP-8); latent form.Matrix metalloproteinase 8 (MMP-8); or neutrophil collagenase; degrades interstitial collagens; acting preferentially on collagen type I. Increased full-length MMP-8 protein was associated with infiltration into the skin of neutrophils; which are the major cell type that expresses MMP-8.MMP-8 is synthesized and stored in specific granules in neutrophil leukocytes. MMP-8 activity is therefore regulated by factors such as surface-bound ligands (IgG or complement components) that release it through degranulation.Once released and activated through proteolytic or oxidative mechanisms; MMP-8 plays a major role in the connective tissue turnover that accompanies inflammatory processes.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Assay Kits:MMP
- Manufacturer's Data Sheet:1.jpg
