MMP 7 Recombinant Protein
Product Sizes
20 µg
£528.00
32-2551-20UG
About this Product
- SKU:
- 32-2551
- Additional Names:
- Matrilysin||EC 3.4.24.23||Pump-1 protease||Uterine metalloproteinase||Matrix metalloproteinase-7||MMP-7||Matrin||MPSL1||PUMP-1||MMP7.
- Extra Details:
- Source : Escherichia Coli. Matrix Metalloproteinase-7 Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing having a molecular mass of 19.13 kDa.The MMP-7 is purified by proprietary chromatographic techniques. Matrix metalloproteinase-7 (MMP-7) also known as matrilysin and PUMP (EC 3.4.24.23) cleaves a number of substrates including collagen types IV and X; elastin; fibronectin; gelatin; laminin and proteoglycans. MMP-7 is closely related to the stromelysin family members but is encoded by a different gene. MMP-7 is the smallest of all the MMPs consisting of a pro-peptide domain and a catalytic domain. It lacks the hemopexin-like domain common to other members of the MMPs. MMP-7 is secreted as a 28 kDa proenzyme and can be activated in vitro by organomercurials and trypsin and in vivo by MMP-3 to a 18 kDa active MMP-7 enzyme. Once activated; MMP-7 can activate pro-MMP-1 and pro-MMP-9 but not pro-MMP-2. MMP-7 is widely expressed having been reported in elevated levels in cycling endometrium as well as in colorectal cancers and adenomas; hepatocellular carcinomas; rectal carcinomas; and approximately 50% of gliomas.
- Purification:
- Greater than 95.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Matrilysin although stable at 4[o]C for 3 weeks; should be stored desiccated below -18[o]C. Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Assay Kits:MMP
- Manufacturer's Data Sheet:1.jpg
