MMP 3 HEK Recombinant Protein
Product Sizes
10 µg
£528.00
32-2548-10UG
About this Product
- SKU:
- 32-2548
- Additional Names:
- Stromelysin-1||EC 3.4.24.17||Matrix metalloproteinase-3||MMP-3||Transin-1||SL-1||STMY||STR1||STMY1||MGC126102||MGC126103||MGC126104.
- Extra Details:
- Source : HEK293 cells. MMP-3 Human Recombinant produced in HEK293 cells is a proform of the Human MMP3 [Tyr18-Cys477 (Lys45Glu)] and fused with a ployhistide tag at the C-terminus; having an Mw of 52kDa. MMP-3 is purified by proprietary chromatographic techniques. MMP-3 enzyme is also known as Stromelysin-1or as Transin-1 which hydrolyzes natural collagen at physiological pH and temperature. It dissolves the intervertebral nucleus pulposus and annulus fibrosus of Herniated Lumbar Intervertebral Disk . MMP-3 hydrolyzes components of the extracellular matrix like proteoglycan; laminin; fibronectin; gelatin and collagen types III; IV and IX. It also activates pro-MMP-9 and pro-MMP-8 and superactivates plasmin activated MMP-1. MMP-3 is secreted as a latent proenzyme and is activated by a variety of proteinases; e.g. plasmin; trypsin; chymotrypsin; cathepsin G or human neutrophil elastase. MMP-3 was found to be capable of activating the precursor of IL1-beta.
- Purification:
- Greater than 95% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Assay Kits:MMP
- Manufacturer's Data Sheet:1.jpg
