MMP 13 Recombinant Protein
Product Sizes
10 µg
£528.00
32-2545-10UG
About this Product
- SKU:
- 32-2545
- Additional Names:
- CLG3||MANDP1||Collagenase 3||Matrix metalloproteinase-13||MMP-13||MMP13.
- Extra Details:
- Source : Escherichia Coli. MMP-13 produced in E.Coli is a single; non-glycosylated polypeptide chain containing 391 amino acids (104-471 a.a.) and having a molecular mass of 44.7 kDa. MMP-13 is fused to a 23 amino acid His Tag at N-Terminus and purified by proprietary chromatographic techniques. Latent recombinant human pro-collagenase (MMP-13) also called collagenase-3 truncated from C-terminal.Matrix Metalloproteinase-13 (MMP-13) is an enzyme that is a member of the MMP extracellular protease family. Extracellular protease enzymes; by virtue of their broad substrate specificities1; play a role in both normal and disease states of tissue proliferation. Among the targets of MMP-13 are collagen; gelatin; entactin; pro-TNF-a; and chemokine SDF-11-4.MMP-13 is found in its latent form as a 52-56 kDa glycosylated proenzyme. Upon cleavage the 22-46 kDa5 MMP-1 becomes active in extracellular matrix remodeling.Because of the prominent role that MMP-1 plays in cell migration and metastasis; it is an important target for inhibition screening.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Assay Kits:MMP
- Manufacturer's Data Sheet:1.jpg
