MMP 1 Recombinant Protein
Product Sizes
20 µg
£528.00
32-2544-20UG
About this Product
- SKU:
- 32-2544
- Additional Names:
- CLG||CLGN||Interstitial collagenase||Fibroblast collagenase||Matrix metalloproteinase-1||MMP-1.
- Extra Details:
- Source : Escherichia Coli. MMP 1 Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 393 amino acids (100-469a.a) and having a molecular mass of 45kDa. MMP 1 is fused to a 23 amino acid His-tag at N-terminus. MMP-1 (interstitial collagenase) can break down a wide range of substrates including types I; II; III; VII; VIII; and X collagens as well as L-Selectin; pro-TNF; IL-1; IGFBP-3; IGFBP-5; casein; gelatin; ?1 antitrypsin; myelin basic protein; pro-MMP2 and pro-MMP9. A significant function of MMP-1 is the degradation of fibrillar collagens in extracellular matrix remodeling. MMP-1 is expressed in fibroblasts; keratinocytes; endothelial cells; monocytes and macrophages. MMP1 can be divided into a number of distinct domains: a prodomain which is cleaved on activation; a catalytic domain containing the zinc binding site and a short hinge region with a carboxyl terminal domain. MMP1 is part of a cluster of MMP genes which localize to chromosome 11q22.3.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Assay Kits:MMP
- Manufacturer's Data Sheet:1.jpg
