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HMGCL Recombinant Protein

Product Sizes
20 µg
£528.00
32-2441-20UG
About this Product
SKU:
32-2441
Additional Names:
Hydroxymethylglutaryl-CoA lyase mitochondrial||HL||HMG-CoA lyase||3-hydroxy-3-methylglutarate-CoA lyase||HMGCL.
Extra Details:
Source : Escherichia Coli. HMGCL Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 323 amino acids (28-325) and having a molecular mass of 34.2kDa.HMGCL is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Hydroxymethylglutaryl-CoA lyase (HMGCL) is a mitochondrial matrix protein which is a member of the HMG-CoA lyase family. HMGCL is a homodimer and participates in leucine catabolism and ketogenesis; the hepatic synthesis of ketone bodies which; during fasting; provides a major source of energy for the heart; brain and kidney. More precisely; HMGCL catalyzes the final step of these processes; the cleavage of 3-hydroxy-3-methylglutaryl-CoA to acetoacetic acid and acetyl-CoA.
Purification:
Greater than 85.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg