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HAT1 Recombinant Protein

Product Sizes
10 µg
£528.00
32-2429-10UG
About this Product
SKU:
32-2429
Additional Names:
EC 2.3.1.48||KAT1||histone acety ltransferase 1||Histone acetyltransferase type B catalytic subunit||HAT1.
Extra Details:
Source : Escherichia Coli. HAT1 Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 343 amino acids (20-341 a.a.) and having a molecular mass of 40.1 kDa. The HAT1 is fused to a 21 amino acid His Tag and purified by proprietary chromatographic techniques. HAT1 is a type B histone acetyltransferase that participates in the rapid acetylation of newly synthesized cytoplasmic histones; which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation; mainly of soluble histone H4 at ''Lys-5'' and ''Lys-12'' and acetylates histone H2A at ''Lys-5''. HAT1 takes part in replication-dependent chromatin assembly. HAT1 acetylates soluble but not nucleosomal histone H4 at lysines 5 and 12; and to a lesser degree; histone H2A at lysine 5. HAT1 has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.
Purification:
Greater than 90% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
HAT1 Recombinant Human although stable at 4[o]C for 30 days; should be stored below -20[o]C for periods greater than 30 days. Please avoid freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg