GMPS Recombinant Protein
Product Sizes
10 µg
£528.00
32-2378-10UG
About this Product
- SKU:
- 32-2378
- Additional Names:
- GMP synthase [glutamine-hydrolyzing]||GMP synthetase||Glutamine amidotransferase||GMPS||Guanine monphosphate synthetase||GMP synthase||guanosine 5'-monophosphate synthase||MLL/GMPS fusion protein.
- Extra Details:
- Source : Escherichia Coli. GMPS Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 717 amino acids (1-693) and having a molecular mass of 79.2kDa.GMPS is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. GMP synthase (GMPS) is involved in purine biosynthesis. GMPS; which is a homodimer; catalyzes the last step in the GMP synthesis pathway; specifically the ATP-dependent amination of XMP to GMP. GMPS is comprised of one GMP-binding domain and one glutamine amidotransferase type-1 domain through which it communicates its catalytic activity. GMPS is engaged in the de novo synthesis of guanine nucleotides which are not only vital for DNA and RNA synthesis; but also supply GTP; which is involved in sevral cellular processes important for cell division. GMPS gene chromosomal translocations are linked with acute myeloid leukemias; suggesting a possible role for GMPS in carcinogenesis.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
