GLUD1 Recombinant Protein
Product Sizes
20 µg
£528.00
32-2371-20UG
About this Product
- SKU:
- 32-2371
- Additional Names:
- Glutamate Dehydrogenase 1||GLUD||GDH 1||EC 1.4.1.3||GDH||GDH1||Glutamate Dehydrogenase (NAD(P)+)||Glutamate Dehydrogenase 1 Mitochondrial||EC 1.4.1||GLUD1.
- Extra Details:
- Source : Escherichia Coli. GLUD1 Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 528 amino acids (54-558) and having a molecular mass of 58.4kDa.GLUD1 is fused to a 23 amino acid His-tag at N-terminus. Glutamate dehydrogenase 1; mitochondrial precursor (GLUD1) is a member of the Glu/Leu/Phe/Val dehydrogenases family. GLUD1 is a mitochondrial glutamate dehydrogenase; which converts L-glutamate into alpha-ketoglutarate. GLUD1 has a pivotal role in nitrogen metabolism in plants and animals. GLUD1 is observed in all organisms and catalyzes the oxidative deamination of 1-glutamate to 2-oxoglutarate. The GLUD1 enzyme has a vital role in regulating amino acid induced insulin secretion. GLUD1 gene mutations cause hyperinsulinism-hyperammonemia syndrome (HHS); which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 enzyme is allosterically activated by ADP and inhibited by GTP and ATP.
- Purification:
- Greater than 80.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
