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GATM Recombinant Protein

Product Sizes
10 µg
£528.00
32-2350-10UG
About this Product
SKU:
32-2350
Additional Names:
Glycine amidinotransferase||mitochondrial||L-arginine:glycine amidinotransferase||Transamidinase||GATM||AGAT||AT.
Extra Details:
Source : E.coli. GATM Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 410 amino acids (38-423) and having a molecular mass of 46.9kDa (Molecular size on SDS-PAGE will appear higher).GATM is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Glycine amidinotransferase mitochondrial (GATM) is a mitochondrial enzyme which is a member of the amidinotransferase family. The GATM enzyme is involved in creatine biosynthesis; where it catalyzes the transfer of a guanido group from L-arginine to glycine; resulting in guanidinoacetic acid; the immediate precursor of creatine; which has an imperative role in energy metabolism in muscle tissues. GATM is significant in embryonic and central nervous system development. GATM gene mutations cause arginine:glycine amidinotransferase deficiency; an inborn error of creatine synthesis characterized by mental retardation; language impairment; and behavioral disorders.
Purification:
Greater than 90% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg