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GAMT Recombinant Protein

Product Sizes
25 µg
£528.00
32-2347-25UG
About this Product
SKU:
32-2347
Additional Names:
PIG2||TP53I2||GAMT||Guanidinoacetate N-methyltransferase.
Extra Details:
Source : Escherichia Coli. Recombinant Human GAMT produced in E.Coli is a single; non-glycosylated polypeptide chain containing 256 amino acids (1-236 a.a) and having a molecular mass of 28.4 kDa. GAMT is fused to 20 amino acid His-Tag at N-terminus and purified by conventional chromatography techniques. GAMT is a methyltransferase that transfers guanidoacetate to creatine; using S-adenosylmethionine as the methyl donor. Defects GAMT gene result in neurologic syndromes and muscular hypotonia; probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. GAMT take parts in the two-step synthesis of creatine from the protein building blocks glycine; arginine; and methionine. GAMT takes part in supplying the energy for muscle contraction; and is in addition a significant player in nervous system functioning. GAMT is active in the liver; pancreas; and kidne.
Purification:
Greater than 95.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg