GAD1 iso1 Recombinant Protein
Product Sizes
20 µg
£528.00
32-2343-20UG
About this Product
- SKU:
- 32-2343
- Additional Names:
- Glutamate Decarboxylase 1 (Brain||67kDa)||Glutamate Decarboxylase 67 KDa Isoform||67 KDa Glutamic Acid Decarboxylase||EC 4.1.1.15; GAD-67||CPSQ1||SCP||GAD||Glutamate Decarboxylase 1 (Brain||67kD)||Glutamate Decarboxylase 1||EC 4.1.1||GAD67||Glutamate
- Extra Details:
- Source : E.coli. GAD1 iso1 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 617 amino acids (1-594 a.a) and having a molecular mass of 69.3kDa. GAD1 iso1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Glutamate Decarboxylase 1 Isoform-1; also known as GAD1 iso1 belongs to the group II decarboxylase family. GAD1 iso1 encodes one of several forms of glutamic acid decarboxylase; and is identified as a major autoantigen in insulin-dependent diabetes. GAD1 iso1 is in charge for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. In addition; a pathogenic function for GAD1 iso1 has been shown in the human pancreas while it has been identified as an autoantigen & an autoreactive T cell target in insulin-dependent diabetes. GAD1 iso1 play a role in the stiff man syndrome. It has been shown that deficiency in this enzyme has led to pyridoxine dependency with seizures.
- Purification:
- Greater than 80% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
