GAD1 Recombinant Protein
Product Sizes
10 µg
£528.00
32-2342-10UG
About this Product
- SKU:
- 32-2342
- Additional Names:
- Glutamate Decarboxylase 1 (Brain||67kDa)||GAD||Glutamate Decarboxylase 67 KDa Isoform||67 KDa Glutamic Acid Decarboxylase||GAD-67||EC 4.1.1.15||CPSQ1||SCP||Glutamate Decarboxylase 1 (Brain||67kD)||Glutamate Decarboxylase 1||GAD67||EC 4.1.1||GAD1.
- Extra Details:
- Source : E.coli. GAD1 Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 247 amino acids (1-224) and having a molecular mass of 27.7kDa.GAD1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Glutamate Decarboxylase 1 (GAD1) is one of several forms of glutamic acid decarboxylase; known as a key autoantigen in insulin-dependent diabetes. GAD1 is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for the GAD1 enzyme has been identified in the human pancreas since it has been detected as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. The GAD1 protein may also have a role in the stiff man syndrome. GAD1 enzyme deficiency leads to pyridoxine dependency with seizures. GAD1 also catalyzes the production of GABA.
- Purification:
- Greater than 85% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
