GARS Recombinant Protein
Product Sizes
10 µg
£528.00
32-2337-10UG
About this Product
- SKU:
- 32-2337
- Additional Names:
- Glycine--tRNA ligase||Diadenosine tetraphosphate synthetase||AP-4-A synthetase||Glycyl-tRNA synthetase||GlyRS||GARS||CMT2D||DSMAV||HMN5||SMAD1.
- Extra Details:
- Source : Escherichia Coli. GARS Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 270 amino acids (43-289 a.a) and having a molecular mass of 30kDa.GARS is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. GARS is an (alpha)2 dimer which is a member of the class II family of tRNA synthetases. GARS is a glycyl-tRNA synthetase; one of the aminoacyl-tRNA synthetases which charge tRNAs with their cognate amino acids. GARS catalyzes the attachment of glycine to tRNA(Gly). In addition; GARS is able to produce diadenosine tetraphosphate (Ap4A); which is a universal pleiotropic signaling molecule required for cell regulation pathways; by direct condensation of two ATPs. GARS has been demonstrated to be a target of autoantibodies in the human autoimmune diseases; polymyositis or dermatomyositis.
- Purification:
- Greater than 85.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
