FTCD Recombinant Protein
Product Sizes
10 µg
£452.00
32-2331-10UG
About this Product
- SKU:
- 32-2331
- Additional Names:
- Formiminotransferase-cyclodeaminase||FTCD||LCHC1||LC-1.
- Extra Details:
- Source : Sf9 insect cells. Formiminotransferase Cyclodeaminase Human Recombinant (also called liver cytosol type 1) produced in SF9; is a glycosylated; polypeptide chain having a molecular mass of 59;749 Dalton.The FTCD is expressed with a -6xHis tag and purified by proprietary chromatographic techniques. Formiminotransferase cyclodeaminase is an enzyme which catalyzes the conversion of formiminoglutamateand tetrahydrofolateinto formiminotetrahydrofolateand glutamate.Formiminotransferase cyclodeaminase; a bifunctional enzyme of tetrahydrofolate synthesis; is the target antigen of anti-LC1 (liver cytosol antigen type 1) autoantibodies. Presence of LC1 autoantibodies is a marker for type 2 autoimmune hepatitis (for which anti-LKM 1/cytochrome P450 2D6 autoantibodies are a further marker).Serum LC1 autoantibody concentrations appear to fluctuate in parallel with aminotransferase levels; a particularly intriguing observation that suggests a possible role of LC1 autoreactivity in the pathogenic mechanism leading to hepatocyte injury.
- Purification:
- Greater than 95% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]Cfor longer periods of time. Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
