FKBP3 Recombinant Protein
Product Sizes
20 µg
£528.00
32-2327-20UG
About this Product
- SKU:
- 32-2327
- Additional Names:
- EC 5.2.1.8||FKBP-3||FKBP25||FKBP-25||Peptidyl-prolyl cis-trans isomerase FKBP3||PPIase FKBP3||FK506-binding protein 3||Rotamase||Immunophilin FKBP25||25 kDa FK506-binding protein||25 kDa FKBP||Rapamycin-selective 25 kDa immunophilin||FKBP3||PPIase.
- Extra Details:
- Source : Escherichia Coli. FKBP3 produced in E.Coli is a single; non-glycosylated polypeptide chain containing 224 amino acids (1-224 a.a.) and having a molecular mass of 25.1 kDa. FKBP3 is purified by proprietary chromatographic techniques. FKBP3 is part of a family of immunosuppressant receptors which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 accelerates the folding of proteins. FKBP3 is part of the immunophilin protein family; which participates in immunoregulation and fundamental cellular processes concerning protein folding and trafficking. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin; as well as histone deacetylases; the transcription factor YY1; casein kinase II; and nucleolin. It has a greater affinity for rapamycin than for FK506 and therefore is a significant protein for immunosuppression by rapamycin.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
