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DTD1 Recombinant Protein

Product Sizes
10 µg
£528.00
32-2285-10UG
About this Product
SKU:
32-2285
Additional Names:
bA379J5.3||bA555E18.1||C20orf88||DUEB||HARS2||pqn-68||D-tyrosyl-tRNA(Tyr) deacylase 1||DNA-unwinding element-binding protein B.
Extra Details:
Source : Escherichia Coli. DTD1 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 232 amino acids (1-209a.a.) and having a molecular mass of 25.9kDa.DTD1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. D-Tyrosyl-tRNA Deacylase 1 (DTD1) is a member of the DTD family. DTD1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). DTD1 may be a defense mechanism against a damaging effect of D-tyrosine. DTD1 is an ATPase involved in DNA replication; which may facilitate loading of CDC45 onto pre-replication complexes. The DTD1 protein localizes to the DUE (DNA unwinding elements) of active replication origins. DTD1 is expressed in numerous adult and fetal tissues; with the highest levels in the testis; ovary; spleen and in the adult and fetal brain. DTD1 might be a risk factor for AIA (aspirin-intolerant asthma) by catalyzing the hydrolysis of D-tryptophan and interacting with the tyrosyl-tRNA synthetase (tyrRS) enzyme that promotes a pro-inflammatory phenotype.
Purification:
Greater than 85% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg