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DPP4 Recombinant Protein

Product Sizes
10 µg
£528.00
32-2281-10UG
About this Product
SKU:
32-2281
Additional Names:
CD26||ADABP||ADCP2||DPPIV||TP103||DPP4||Dipeptidyl peptidase 4||Dipeptidyl peptidase IV||DPP IV||T-cell activation antigen CD26||Adenosine deaminase complexing protein 2||CD26 antigen.
Extra Details:
Source : High-5 cells. DPPIV Human Recombinant produced in High-5 cells is a single; glycosylated polypeptide chain containing 746 amino acids (39-766) and having a molecular mass of 86.4 kDa.DPPIV is fused to His Tag at C-terminus and purified using conventional chromatography techniques. DPP4 also called adenosine deaminase complexing protein-2; and T-cell activation antigen CD26 is a serine exopeptidase and complex enzyme that is expressed on the surface of most cell types. DPPIV is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. DPP4 plays a role in t-cell activation. DPP4 is associated with intracellular signal transduction; apoptosis and involved in tumor biology. There are at least 63 substrates which can bind specifically to DPP4 enzyme including growth factors; chemokines; neuro peptides. Furthermore; DPP4 plays a major role in glucose metabolism by cleaving incretins such as glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1).
Purification:
Greater than 95.0% as determined by Analysis by SDS-PAGE.On SDS-PAGE under denatured condition; apparent molecular weight of glycosylated DPP4 will migrate at approximately 90kDa.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg