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Cyclophilin D Recombinant Protein

Product Sizes
20 µg
£528.00
32-2245-20UG
About this Product
SKU:
32-2245
Additional Names:
Peptidylprolyl isomerase D||PPID||CYPD||CYP-40||40 kDa peptidyl-prolyl cis-trans isomerase||PPIase||Rotamase||Cyclophilin-40||CYP40||Cyclophilin-related protein||MGC33096||EC 5.2.1.8.
Extra Details:
Source : Escherichia Coli. Cyclophilin-D Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain (amino acids 1-370) containing 390 amino acids and having a molecular mass of 42.9kDa. Cyclophilin-D is fused to a 20 aa His Tag at N-terminus and is purified by proprietary chromatographic techniques. Cyclophilin-D is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and speeds up the protein folding. Cyclophilin-D possess PPIase activity and binds to the immunosuppressant cyclosporin-A. Cyclophilin-D is very well known that its overexpression suppresses the apoptosis in cancer cell. Cyclophilin-D suppresses apoptotic cell death by the use of mitochondrial hexokinase-2 dependent mechanism in cancer cells.
Purification:
Greater than 95.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg