CTDSPL Recombinant Protein
Product Sizes
20 µg
£528.00
32-2230-20UG
About this Product
- SKU:
- 32-2230
- Additional Names:
- CTD small phosphatase-like protein||CTDSP-like||Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3||NIF-like protein||Nuclear LIM interactor-interacting factor 1||NLI-interacting factor 1||Protein YA22||hYA22||RBSP3
- Extra Details:
- Source : Escherichia Coli. CTDSPL Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 209 amino acids (82-265) and having a molecular mass of 23.9kDa.CTDSPL is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. CTD small phosphatase-like protein (CTDSPL) specially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the biggest RNA polymerase II subunit POLR2A. CTDSPL negatively regulates RNA polymerase II transcription; probably by directing the transition from initiation/capping to processive transcript elongation. CTDSPL is employed by REST to neuronal genes which contain RE-1 elements; directing to neuronal gene silencing in non-neuronal cells.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
