CTDSP1 Recombinant Protein
Product Sizes
10 µg
£528.00
32-2229-10UG
About this Product
- SKU:
- 32-2229
- Additional Names:
- Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1||Nuclear LIM interactor-interacting factor 3||NLI-IF||NLI-interacting factor 3||Small C-terminal domain phosphatase 1||SCP1||Small CTD phosphatase 1||CTDSP1||NIF3||NLIIF.
- Extra Details:
- Source : Escherichia Coli. CTDSP1 produced in E.Coli is a single; non-glycosylated polypeptide chain containing 280 amino acids (1-260 a.a.) and having a molecular mass of 31.2kDa.CTDSP1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. CTDSP1 is a class 2C phosphatase with activity dependent on the conserved DxD motif. CTDSP1 preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. In addition; CTDSP1 negatively regulates RNA polymerase II transcription; possibly by controlling the transition from initiation/capping to processive transcript elongation.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
