BPNT1 Recombinant Protein
Product Sizes
10 µg
£528.00
32-2194-10UG
About this Product
- SKU:
- 32-2194
- Additional Names:
- 3'(2')||5'-bisphosphate nucleotidase 1||Bisphosphate 3'-nucleotidase 1||PAP-inositol-1;4-phosphatase||PIP||EC 3.1.3.7||BPntase.
- Extra Details:
- Source : Escherichia Coli. BPNT1 produced in E.Coli is a single; non-glycosylated polypeptide chain containing 344 amino acids (1-308a.a.) and having a molecular mass of 37.5kDa.BPNT1 is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. BPNT1 belongs to the magnesium-dependent; lithium-sensitive phosphomono-esterase superfamily. BPNT1 catalyzes the conversion of PAPS (adenosine 3'-phosphate 5' phosphosulfate) to APS (adenosine 5'-phosphosulfate) and the conversion of PAP (3'(2')-phosphoadenosine 5' phosphate) to AMP (adenosine 5'-phosphate) using magnesium as a cofactor. BPNT1 is expressed everywhere but at maximum levels in brain and kidney. BPNT1 is potently inhibited by lithium; a drug used for the treatment of manic depression and bipolar affective disorder; which suggests that BPNT1 has a possible role in the etiology of mood disorders.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.Please avoid freeze thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
