BHMT2 Recombinant Protein
Product Sizes
10 µg
£528.00
32-2188-10UG
About this Product
- SKU:
- 32-2188
- Additional Names:
- BHMT2||Betaine--Homocysteine S-Methyltransferase 2||SMM-Hcy Methyltransferase||Betaine-Homocysteine Methyltransferase 2||S-Methylmethionine--Homocysteine S-Methyltransferase BHMT2||EC 2.1.1.10||EC 2.1.1.5.
- Extra Details:
- Source : Escherichia Coli. BHMT2 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 386 amino acids (1-363 a.a.) and having a molecular mass of 42.7kDa. BHMT2 is fused to a 23 amino acid His-tag at N-terminus. Betaine-Homocysteine Methyltransferase 2 (BHMT2) is involved in the regulation of homocysteine metabolism. Homocysteine is a sulfur-containing amino acid which has a key role in methylation reactions. Transfer of the methyl group from betaine to homocysteine generates methionine; which donates the methyl group to methylate DNA; proteins; lipids; and other intracellular metabolites. BHMT2 is one of two methyl transferases which can catalyze the transfer of the methyl group from betaine to homocysteine. BHMT2 converts homocysteine to methionine using S-methylmethionine (SMM) as a methyl donor. Homocysteine metabolism anomalies are implicated in disorders varying from vascular disease to neural tube birth defects such as spina bifida.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
