ALDH2 Recombinant Protein
Product Sizes
50 µg
£528.00
32-2143-50UG
About this Product
- SKU:
- 32-2143
- Additional Names:
- ALDM||ALDHI||ALDH-E2||MGC1806||ALDH2||Aldehyde dehydrogenase mitochondrial||ALDH class 2.
- Extra Details:
- Source : Escherichia Coli. ALDH2 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 501 amino acids (18-517 a.a.) & having a molecular mass of 54.5 kDa. The ALDH2 is purified by proprietary chromatographic techniques. ALDH2 is part of the aldehyde dehydrogenase family of proteins which catalyze the chemical transformation from acetaldehyde to acetic acid. ALDH2 is the second enzyme of the major oxidative pathway of alcohol metabolism. ALDH2 has 2 major liver isoforms: cytosolic and mitochondrial; which differ by their electrophoretic mobilities; kinetic properties; and subcellular localizations. Nearly all Caucasians have 2 major isozymes; whereas roughly 50% of Orientals have only the cytosolic isozyme; omitting the mitochondrial isozyme. The extremely higher rate of acute alcohol intoxication with Orientals compared to Caucasians is due to the fact of the absence of mitochondrial isozyme. ALDH2 has a low Km for acetaldehydes; and is localized in mitochondrial matrix.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
