ACADSB Recombinant Protein
Product Sizes
10 µg
£528.00
32-2105-10UG
About this Product
- SKU:
- 32-2105
- Additional Names:
- Short/branched chain specific acyl-CoA dehydrogenase mitochondrial||SBCAD||2-methyl branched chain acyl-CoA dehydrogenase||2-MEBCAD||2-methylbutyryl-coenzyme A dehydrogenase||2-methylbutyryl-CoA dehydrogenase||ACADSB||ACAD7||SBCAD||2-MEBCAD.
- Extra Details:
- Source : Escherichia Coli. ACADSB Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 424 amino acids (34-432) and having a molecular mass of 46.4kDa.ACADSB is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Short/branched chain specific acyl-CoA dehydrogenase (ACADSB) belongs to the acyl-CoA dehydrogenase family of enzymes which catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. ACADSB catalyzes the degradation of L-isoleucine while having the highest affinity for (s)-2-methylbutyryl-CoA; isobutyryl-CoA and 2-methylhexanoyl-CoA as substrates. ACADSB may use valproyl-CoA as substrate and have a role in regulating the metabolic flux of valproic acid in the development of toxicity of this agent. ACADSB gene defects cause the short/branched-chain acyl-CoA dehydrogenase deficiency (SBCADD); which is an autosomal recessive disorder characterized by an increase of 2-methylbutyrylglycine and 2-methylbutyrylcarnitine in blood and urine.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
