Platelet factor-4 Native Protein
Product Sizes
20 µg
£528.00
32-1978-20UG
About this Product
- SKU:
- 32-1978
- Additional Names:
- CXCL4||PF-4||PF4||Iroplact||Oncostatin-A||SCYB4||MGC138298.
- Extra Details:
- Source : Human Platelets. Human PF-4 a 7.8 kDa protein consisting of 70 amino acid residues. Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels; thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts; PF4 probably has a role in inflammation and wound repair. Oncostatin-A is a member of the CXC chemokine family. Human PF4 is used for the proof of heparin-induced thrombocytopenia. Furthermore it is used as an inhibitor in the angiogenesis during tumor therapy.
- Purification:
- Greater than 95.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Human CXCL4 although stable at 25[o]C 1 week; should be stored desiccated below -18[o]C. Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
