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MIP 1b Recombinant Protein

Product Sizes
10 µg
£528.00
32-1960-10UG
About this Product
SKU:
32-1960
Additional Names:
Small inducible cytokine A4||CCL4||Macrophage inflammatory protein 1-beta||MIP-1- beta||MIP-1-beta(1-69)||T-cell activation protein 2||ACT-2||PAT 744||H400||SIS-gamma||Lymphocyte activation gene 1 protein||LAG-1||HC21||G-26 T-lymphocyte-secreted prot
Extra Details:
Source : Escherichia Coli. Macrophage Inflammatory Protein-1 beta Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 69 amino acids and having a molecular mass of 7620 Dalton. The CCL4 is purified by proprietary chromatographic techniques. Macrophage Inflammatory Proteins belong to the family of chemotactic cytokines known as chemokines. In humans; there are two major forms; MIP-1a and MIP-1b that are now also named CCL3 and CCL4. Both factors are produced by macrophages after they are stimulated with bacterial endotoxins. MIP-1a and MIP-1b activate human granulocytes (neutrophils; eosinophils and basophils) which can lead to acute neutrophilic inflammation. MIP-1a and MIP-1b induce synthesis and release of other pro-inflammatory cytokines such as interleukin-1 (IL-1); IL-6 and TNF-alpha from fibroblasts and macrophages. CCL3 and CCL4 genes are both located on human chromosome 17.
Purification:
Greater than 99.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Lyophilized MIP-1b although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution CCL4 should be stored at 4[o]C between 2-7 days and for future use below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg