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MIP 1a Recombinant Protein

Product Sizes
20 µg
£528.00
32-1955-20UG
About this Product
SKU:
32-1955
Additional Names:
Small inducible cytokine A3||CCL3||Macrophage inflammatory protein 1-alpha||MIP-1-alpha||Tonsillar lymphocyte LD78 alpha protein||G0/G1 switch regulatory protein 19-1||G0S19-1 protein||SIS-beta||PAT 464.1||chemokine (C-C motif) ligand 3||MIP1A||SCYA3
Extra Details:
Source : Escherichia Coli. Macrophage Inflammatory Protein-1 alpha Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 70 amino acids and having a molecular mass of 7820 Dalton. The MIP-1a is purified by proprietary chromatographic techniques. Macrophage Inflammatory Proteins (MIP) belong to the family of chemotactic cytokines known as chemokines. In humans; there are two major forms; MIP-1a and MIP-1b that are now officially named CCL3 and CCL4 respectively. Both are major factors produced by macrophages after they are stimulated with bacterial endotoxins. They activate human granulocytes (neutrophils; eosinophilsand basophils) which can lead to acute neutrophilic inflammation. They also induce the synthesis and release of other pro-inflammatory cytokines such as interleukin 1 (IL-1); IL-6 and TNF-a from fibroblasts and macrophages. The genes for CCL3 and CCL4 are both located on human chromosome 17.
Purification:
Greater than 98.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Lyophilized MIP-1a although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution CCL3 should be stored at 4[o]C between 2-7 days and for future use below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg