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mMCP-2 Recombinant Protein

Product Sizes
10 µg
£528.00
32-1937-10UG
About this Product
SKU:
32-1937
Additional Names:
Small inducible cytokine A8||CCL8||Monocyte chemotactic protein 2||MCP-2||Monocyte chemoattractant protein 2||HC14||chemokine (C-C motif) ligand 8||MCP2||SCYA8||SCYA10||AB023418||1810063B20Rik.
Extra Details:
Source : Escherichia Coli. Monocyte Chemotactic Protein-2 Mouse Recombinant produced in E.Coli is a non-glycosylated; Polypeptide chain containing 74 amino acids and having a molecular mass of 8507 Dalton. The MCP-2 is purified by proprietary chromatographic techniques. Chemokine (C-C motif) ligand 8 (CCL8) is a small cytokine belonging to the CC chemokine family that was once called monocyte chemotactic protein-2 (MCP-2). The CCL8 protein is produced as a precursor containing 109 amino acids; which is cleaved to produce mature CCL8 containing 75 amino acids. The gene for CCL8 is encoded by 3 exons and is located within a large cluster of CC chemokines on chromosome 17q11.2 in humans. MCP-2 is chemotactic for and activates a many different immune cells; including mast cells; eosinophils and basophils; (that are implicated in allergic responses); and monocytes; T cells; and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors called chemokine receptors. These receptors include CCR1; CCR2B and CCR5.
Purification:
Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Lyophilized MCP-2 although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution CCL8 should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg