MCP 1 Recombinant Protein
Product Sizes
20 µg
£528.00
32-1931-20UG
About this Product
- SKU:
- 32-1931
- Additional Names:
- Small inducible cytokine A2||CCL2||Monocyte chemotactic protein 1||MCP-1||Monocyte chemoattractant protein 1||Monocyte chemotactic and activating factor||MCAF||Monocyte secretory protein JE||HC11||chemokine (C-C motif) ligand 2||MCP1||SCYA2||GDCF-2||
- Extra Details:
- Source : Escherichia Coli. Monocyte Chemotactic Protein-1 Human Recombinant also known as Monocyte Chemotactic and Activating Factor (MCAF) produced in E.Coli is a non-glycosylated; Polypeptide chain containing 76 amino acids and having a molecular mass of 8.6kDa. The MCP-1 is purified by proprietary chromatographic techniques. Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). It is found at the site of tooth eruption and bone degradation. In the bone; CCL2 is expressed by mature osteoclasts and osteoblasts and is under the control of nuclear factor B (NFB). CCL2 recruits immune cells; such as monocytes; to sites of tissue injury and infection. This chemokine is produced as a protein precursor containing signal peptide of 23 amino acids and a mature peptide of 76 amino acids. It is a monomeric polypeptide; with a molecular weight of approximately 13kDa. As with many other CC chemokines; CCL2 is located on chromosome 17 in humans. The cell surface receptors that bind CCL2 are CCR2 and CCR5.
- Purification:
- Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized MCP-1 although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution CCL2 should be stored at 4[o]C between 2-7 days and for future use below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
