TNF-alpha (human) (multimeric) (Recombinant)
Product Sizes
10 µg
£458.00
32-190048-10UG
About this Product
- SKU:
- 32-190048
- Additional Names:
- MultimericTNF-alphaâ„¢; ACRP30headless:TNF-alpha; ACRP30headless:TNFSF2; ACRP30headless:Tumor Necrosis Factor-alpha
- Extra Details:
- Source :HEK 293 cells Specific Binds to human and mouse TNF-R1 and TNF-R2.Tumor necrosis factor (TNF; cachexin or cachectin and formerly known as tumor necrosis factor-alpha) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. MultimericTNF-alphaâ„¢ is a high activity construct in which two trimeric TNF-alpha ligands are artificially linked via the collagen domain of ACRP30. The receptor TNF-R1 is activated by both the membrane-bound and soluble trimeric forms of TNF-alpha; whereas the receptor TNF-R2 only responds to the membrane-bound form of TNF-alpha (TNF-alpha (human) (multimeric) (rec.) (32-190048). Since the MultimericTNF-alphaâ„¢ mimics the membrane-bound form (forms oligomers higher than trimer); it is the only TNF-alpha protein that can activate the TNF-R2. For TNF-R1 activation; either normal" TNF-alpha or MultimericTNF-alphaâ„¢ can be used."
- Purification:
- >=95% (SDS-PAGE)
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Short Term Storage +4[o]C ; Long Term Storage-20[o]C ;After reconstitution; prepare aliquots and store at -20[o]C. Avoid freeze/thaw cycles. PBS containing at least 0. 1% BSA should be used for further dilutions. Stable for at least 6 months after receipt when stored at -20[o]C. Working aliquots are stable for up to 3 months when stored at -20[o]C.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
