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Proteins and Peptides

TNF-alpha; Soluble (human) (Recombinant)

Product Sizes
10 µg
£389.00
32-190047-10UG
50 µg
£458.00
32-190047-50UG
About this Product
SKU:
32-190047
Additional Names:
Tumor Necrosis Factor Ligand Superfamily Member 2; Cachectin
Extra Details:
A FLAG®-tag is fused at the N-terminus of human TNF-alpha (aa 85-223).Specific Binds to human and mouse TNF-R1.Tumor necrosis factor (TNF; cachexin or cachectin and formerly known as tumor necrosis factor-alpha) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. The receptor TNF-R1 is activated by both the membrane-bound and soluble trimeric forms of TNF-alpha; whereas the receptor TNF-R2 only responds to the membrane-bound form of TNF-alpha (MultimericTNF-alpha (32-190048). Since the MultimericTNF-alpha mimics the membrane-bound form (forms oligomers higher than trimer); it is the only TNF-alpha protein that can activate the TNF-R2. For TNF-R1 activation; either normal" TNF-alpha or Multimeric TNF-alpha can be used."
Purification:
>=95% (SDS-PAGE)
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Short Term Storage +4[o]C ; Long Term Storage-20[o]C ;After reconstitution; prepare aliquots and store at -20[o]C. Avoid freeze/thaw cycles. PBS containing at least 0. 1% BSA should be used for further dilutions. Stable for at least 6 months after receipt when stored at -20[o]C. Working aliquots are stable for up to 3 months when stored at -20[o]C.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
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