Human ACE2 Protein (FLAG Tag) Biotinylated
Product Sizes
50 µg
£609.00
32-190010-B-50UG
About this Product
- SKU:
- 32-190010-B
- Additional Names:
- SARS Receptor; Angiotensin-converting Enzyme 2; ACEH; Metalloprotease MPROT15; SARS-CoV-2 Receptor
- Conjugate:
- Biotin
- Extra Details:
- Source: HEK 293 cells. Angiotensin-converting enzyme 2 (ACE2) is an ectoenzyme (carboxypeptidase) with an extracellular catalytic domain that predominantly localizes at the plasma membrane and is thereby able to hydrolyze circulating peptides. ACE2 has approximately 42% sequence identity with ACE; and its cytoplasmic and transmembrane domains show 48% homology to the protein collectrin that plays a critical role in the amino acid absorption of the kidney. ACE2 converts angiotensin I to angiotensin 1-9; a peptide of unknown function; and angiotensin II to angiotensin 1-7; a vasodilator. ACE2 is involved in the regulation of systemic blood pressure and has direct effects on cardiac functions. It is expressed predominantly in endothelial cells of the lung; gut; heart and kidney. ACE2 together with the protease TMPRSS2 acts as a functional receptor for SARS coronavirus as well as for the new highly pathogenic coronavirus; 2019-nCoV/SARS-CoV-2; which is cause for pneumonia COVID-19.
- Purification:
- >=95% (SDS-PAGE)
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Short Term Storage +4[o]C. Long Term Storage -20[o]C. After opening; prepare aliquots and store at -20[o]C. Avoid freeze/thaw cycles. For maximum product recovery after thawing; centrifuge the vial before opening the cap. Stable for at least 6 months after receipt when stored at -20[o]C. Working aliquots are stable for up to 3 months when stored at -20[o]C.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
