CXCL17 His Recombinant Protein
Product Sizes
10 µg
£528.00
32-1868-10UG
About this Product
- SKU:
- 32-1868
- Additional Names:
- Dcip1||DMC||MGC138300||UNQ473||VCC-1||VCC1||VEGF coregulated chemokine 1||C-X-C motif chemokine 17||Dendritic cell and monocyte chemokine-like protein.
- Extra Details:
- Source : Escherichia Coli. CXCL17 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 119 amino acids (22-119 a.a) and having a molecular mass of 13.7kDa.CXCL17 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Dendritic cell and monocyte chemokinelike protein (DMC/CXCL17/VEGF-correlated chemokine 1/VCC1); is a secreted molecule with a size and predicted 3-dimensional folding pattern similar to that of chemokines CXCL8/IL8 and CXCL14/BRAK. CXCL17 is constitutively generated by airway and intestinal epithelium. CXCL17 induces the chemotaxis of quiescent; but not LPS-activated peripheral blood monocytes and dendritic cells; and it also binds these cells specifically. The expression of CXCL17 is increased in endothelial cells when they are induced to form tubes in vitro. CXCL17; CXCL1/GRO and CXCL8/IL8 which have roles in angiogenesis; show significantly correlated expression with that of VEGF in primary lung; breast and esophageal tumors. Therefore; CXCL17 is suggested to have a role in tumor angiogenesis. The mature Rat CXCL17 shares 82%; 71% amino acid sequence identity with mouse; human CXCL17; respectively.
- Purification:
- Greater than 85.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
