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CXCL17 Recombinant Protein

Product Sizes
25 µg
£528.00
32-1867-25UG
About this Product
SKU:
32-1867
Additional Names:
VEGF coregulated chemokine 1||C-X-C motif chemokine 17||Dendritic cell and monocyte chemokine-like protein||DMC||CXCL17||VCC1||Dcip1||VCC-1||UNQ473.
Extra Details:
Source : Escherichia Coli. CXCL17 Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 98 amino acids and having a molecular mass of 11.5kDa.The CXCL17 is purified by proprietary chromatographic techniques. Dendritic cell and monocyte chemokinelike protein (DMC/CXCL17/VEGF-correlated chemokine 1/VCC1); is a secreted molecule with a size and predicted 3-dimensional folding pattern similar to that of chemokines CXCL8/IL8 and CXCL14/BRAK. CXCL17 is constitutively generated by airway and intestinal epithelium. CXCL17 induces the chemotaxis of quiescent; but not LPS-activated peripheral blood monocytes and dendritic cells; and it also binds these cells specifically. The expression of CXCL17 is increased in endothelial cells when they are induced to form tubes in vitro. CXCL17; CXCL1/GRO and CXCL8/IL8 which have roles in angiogenesis; show significantly correlated expression with that of VEGF in primary lung; breast and esophageal tumors. Therefore; CXCL17 is suggested to have a role in tumor angiogenesis. The mature Rat CXCL17 shares 82%; 71% amino acid sequence identity with mouse; human CXCL17; respectively.
Purification:
Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Lyophilized CXCL17 although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution CXCL17 should be stored at 4[o]C between 2-7 days and for future use below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg