Human SEMA4A Protein; His Tag
Product Sizes
10µg
£414.00
32-18616-10UG
50 µg
£598.00
32-18616-50UG
About this Product
- SKU:
- 32-18616
- Additional Names:
- RP35; SEMB; SEMAB; CORD10;Recombinant human SEMA4A Protein with C-terminal 10?His tag
- Extra Details:
- This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions; including axon guidance; morphogenesis; carcinogenesis; and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain; a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq; Sep 2010]Molecular Weight : The protein has a predicted molecular mass of 73.3 kDa after removal of the signal peptide. The apparent molecular mass of SEMA4A-His is approximately 70-100 kDa due to glycosylation.Tag :C-10?His tag
- Host:
- HEK293
- Purification:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
