Human CTSL Protein; His Tag
Product Sizes
10µg
£407.00
32-18606-10UG
50 µg
£570.00
32-18606-50UG
About this Product
- SKU:
- 32-18606
- Additional Names:
- MEP; CATL; CTSL1;Recombinant human CTSL Protein with C-terminal 10?His tag
- Extra Details:
- The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin; as well as alpha-1 protease inhibitor; a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes; including myofibril necrosis in myopathies and in myocardial ischemia; and in the renal tubular response to proteinuria. This protein; which is a member of the peptidase C1 family; is a dimer composed of disulfide-linked heavy and light chains; both produced from a single protein precursor. Additionally; this protein cleaves the S1 subunit of the SARS-CoV-2 spike protein; which is necessary for entry of the virus into the cell. [provided by RefSeq; Aug 2020]Molecular Weight : The protein has a predicted molecular mass of 37.2 kDa after removal of the signal peptide. The apparent molecular mass of CTSL-His is approximately 35-55 kDa due to glycosylation.Tag :C-10?His tag
- Host:
- HEK293
- Purification:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
