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Human CD4 Protein; His Tag

Product Sizes
10µg
£394.00
32-18594-10UG
50 µg
£539.00
32-18594-50UG
About this Product
SKU:
32-18594
Additional Names:
T4; IMD79; Leu-3; OKT4D; CD4mut;Recombinant human CD4 Protein with C-terminal 6?His tag
Extra Details:
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes; but also in B cells; macrophages; granulocytes; as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation; and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq; May 2020]Molecular Weight : The protein has a predicted molecular mass of 42.1 kDa after removal of the signal peptide. The apparent molecular mass of CD4-His is approximately 35-55 kDa due to glycosylation.Tag :C-6?His tag
Host:
HEK293
Purification:
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg