Human ACVR2B(67-87) Protein; mFc Tag
Product Sizes
10µg
£411.00
32-18572-10UG
50 µg
£578.00
32-18572-50UG
About this Product
- SKU:
- 32-18572
- Additional Names:
- HTX4; ACTRIIB; ActR-IIB;Recombinant human ACVR2B(67-87) Protein with C-terminal mouse Fc tag
- Extra Details:
- Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins; composed of a ligand-binding extracellular domain with cysteine-rich region; a transmembrane domain; and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding; resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor; which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq; Jul 2008]Molecular Weight : The protein has a predicted molecular mass of 28.7 kDa after removal of the signal peptide. The apparent molecular mass of ACVR2B(67-87)-mFc is approximately 25-35 kDa due to glycosylation.Tag :C-Mouse Fc tag
- Host:
- HEK293
- Purification:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
