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Human ACVR2A(68-88) Protein; mFc Tag

Product Sizes
10µg
£411.00
32-18571-10UG
50 µg
£578.00
32-18571-50UG
About this Product
SKU:
32-18571
Additional Names:
ACVR2; ACTRII;Recombinant human ACVR2A(68-88) Protein with C-terminal mouse Fc tag
Extra Details:
This gene encodes a receptor that mediates the functions of activins; which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain; a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia; a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq; Jun 2013]Molecular Weight : The protein has a predicted molecular mass of 28.7 kDa after removal of the signal peptide. The apparent molecular mass of ACVR2A(68-88)-mFc is approximately 25-35 kDa due to glycosylation.Tag :C-Mouse Fc tag
Host:
HEK293
Purification:
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg