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Cynomolgus CLDN18.2 Protein; hFc Tag

Product Sizes
50 µg
£768.00
32-18495-50UG
100 µg
£952.00
32-18495-100UG
About this Product
SKU:
32-18495
Additional Names:
SFTA5; SFTPJ
Extra Details:
Description :Recombinant Cynomolgus CLDN18.2 protein with N-terminal human Fc tagBackground : This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets; and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. Molecular Characterization: mass of 31.9 kDa after removal of the signal peptide.Tag :N-Human Fc tag
Host:
HEK293
Purification:
The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg