Cynomolgus PD-L1 Protein; His Tag
Product Sizes
50 µg
£744.00
32-18466-50UG
100 µg
£913.00
32-18466-100UG
About this Product
- SKU:
- 32-18466
- Additional Names:
- B7-H; B7H1; PDL1; CD274; hPD-L1; PDCD1L1; PDCD1LG1
- Extra Details:
- Description :Recombinant Cynomolgus PD-L1 protein with C-terminal 10×His tagBackground : This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells; such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue; this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments; this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies; including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. Molecular Characterization: mass of 26.6 kDa after removal of the signal peptide. The apparent molecular mass of cPD-L1-His is approximately 35-55 kDa due to glycosylation.Tag :C-10×His tag
- Host:
- HEK293
- Purification:
- The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
