Human SAP Protein; His Tag
Product Sizes
50 µg
£621.00
32-18374-50UG
100 µg
£731.00
32-18374-100UG
About this Product
- SKU:
- 32-18374
- Additional Names:
- GLBA; SAP1; SAP2; PSAPD; PARK24; PSAP
- Extra Details:
- Description :Recombinant human SAP Protein with C-terminal6Ã-His tagBackground : This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A; B; C; and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants; at least one of which encodes an isoform that is proteolytically processed. Molecular Characterization: mass of 57.3 kDa after removal of the signal peptide. The apparent molecular mass of SAP-His is approximately 55-70 kDa due to glycosylation.Tag :C-6×His tag
- Host:
- HEK293
- Purification:
- The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
