Human RAMP1 Protein; mFc Tag
Product Sizes
50 µg
£654.00
32-18357-50UG
100 µg
£781.00
32-18357-100UG
About this Product
- SKU:
- 32-18357
- Additional Names:
- RAMP1
- Extra Details:
- Description :Recombinant human RAMP1 Protein with C-terminal mouse Fc tagBackground : The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins; called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR; a receptor with seven transmembrane domains; can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor; depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein; CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation; maturation; and presentation of the CGRP receptor to the cell surface. Alternative splicing results in multiple transcript variants encoding different isoforms. Molecular Characterization: mass of 36.7 kDa after removal of the signal peptide. The apparent molecular mass of RAMP1-mFc is approximately 35-55 kDa due to glycosylation.Tag :C-mouse Fc tag
- Host:
- HEK293
- Purification:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
