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Human CFH Protein; His Tag

Product Sizes
50 µg
£634.00
32-18328-50UG
100 µg
£750.00
32-18328-100UG
About this Product
SKU:
32-18328
Additional Names:
FH;HF;HF1;HF2;HUS;FHL1;AHUS1;AMBP1;ARMD4;ARMS1;CFHL3
Extra Details:
Description :Recombinant human CFH Protein with C-terminal 10×His tagBackground : This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation; restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants; encoding different isoforms; have been characterized. Molecular Characterization: mass of 138.4 kDa after removal of the signal peptide. The apparent molecular mass of CFH-His is approximately 130-250 kDa due to glycosylation.Tag :C-10×His Tag
Host:
HEK293
Purification:
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg