Human PLAT Protein; His Tag
Product Sizes
50 µg
£634.00
32-18296-50UG
100 µg
£750.00
32-18296-100UG
About this Product
- SKU:
- 32-18296
- Additional Names:
- T-PA;TPA
- Extra Details:
- Description :Recombinant Human PLAT Protein with C-terminal6Ã-His tagBackground : This gene encodes tissue-type plasminogen activator; a secreted serine protease that converts the proenzyme plasminogen to plasmin; a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis; which manifests as excessive bleeding; while decreased activity leads to hypofibrinolysis; which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants; at least one of which encodes an isoform that is proteolytically processed. Molecular Characterization: mass of 59.9 kDa after removal of the signal peptide. The apparent molecular mass of PLAT-His is approximately 55-70 kDa due to glycosylation.Tag :C-6×His Tag
- Host:
- HEK293
- Purification:
- The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
