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Human CFD Protein; hFc Tag

Product Sizes
50 µg
£621.00
32-18294-50UG
100 µg
£731.00
32-18294-100UG
About this Product
SKU:
32-18294
Additional Names:
ADIPSIN;ADN;DF;PFD
Extra Details:
Description :Recombinant Human CFD Protein with C-terminal human Fc tagBackground : This gene encodes a member of the S1; or chymotrypsin; family of serine peptidases. This protease catalyzes the cleavage of factor B; the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine; a cell signaling protein secreted by adipocytes; which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency; which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. Molecular Characterization: mass of 50.5 kDa after removal of the signal peptide. The apparent molecular mass of CFD-hFc is approximately 55-70 kDa due to glycosylation.Tag :C-Human Fc Tag
Host:
HEK293
Purification:
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg