Human ARTN Protein; hFc Tag
Product Sizes
50 µg
£634.00
32-18277-50UG
100 µg
£750.00
32-18277-100UG
About this Product
- SKU:
- 32-18277
- Additional Names:
- ART;EVN;NBN;ENOVIN
- Extra Details:
- Description :Recombinant Human ARTN Protein with C-terminal human Fc tag Background : This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor; and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth; metastasis; and drug resistance in mammary carcinoma. Molecular Characterization: mass of 38.1 kDa after removal of the signal peptide. The apparent molecular mass of ARTN-hFc is approximately 35-55 kDa due to glycosylation. Tag :C-Human Fc Tag
- Host:
- HEK293
- Purification:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
