Human IL21R Protein; mFc Tag
Product Sizes
50 µg
£680.00
32-18258-50UG
100 µg
£815.00
32-18258-100UG
About this Product
- SKU:
- 32-18258
- Additional Names:
- CD360;IMD56;NILR
- Extra Details:
- Description :Recombinant Human IL21R with C-terminal mouse Fc tag Background : The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors; and has been shown to form a heterodimeric receptor complex with the common gamma-chain; a receptor subunit also shared by the receptors for interleukin 2; 4; 7; 9; and 15. This receptor transduces the growth promoting signal of IL21; and is important for the proliferation and differentiation of T cells; B cells; and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules; including JAK1; JAK3; STAT1; and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. Molecular Characterization: mass of 50.7 kDa after removal of the signal peptide.The apparent molecular mass of IL21R-mFc is approximately 55-70 kDa due to glycosylation. Tag :C-Mouse Fc Tag
- Host:
- HEK293
- Purification:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
